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Neutralization of TNF alpha in one of these models improves insulin sensitivity by increasing the activity of the insulin receptor tyrosine kinase, specifically in muscle and fat tissues.
Conversely, GEN significantly reduced HG induced ROS levels Figure 2.
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Data on hyperglycemia included biochemical data fasting glucose, glycated hemoglobin A1c and medications used for management of DM.
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The patient was still randomly assigned to either one of the two protocols as described previously.
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We would like to acknowledge our colleagues in the pituitary adrenal gonadal subdivision of the Division of Endocrinology, and our adrenal and pituitary surgical colleagues who expertly manage patients with CS.
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