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Aldosterone decreased G6PD expression by increasing expression of the cAMP response element modulator CREM , thereby inhibiting cAMP response element binding protein CREB mediated G6PD transcription.
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Using a PCR based technique, MacDonald et al determined the nucleotide sequence of the entire coding region of the G6PD gene from a person with severe red cell G6PD deficiency and chronic hemolytic anemia.
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In a male with G6PD deficiency from the Dalmatian region of southern Croatia, Barisic et al identified a 1442C G transversion in the G6PD gene, resulting in a pro481 to arg substitution.
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Initially, is 200 blood sugar high the complex is formed by the reversible reaction between the enzyme and specific analyte, which resulted in the desired product with subsequent release of an enzyme.